SIRT1 modulation as a novel approach to the treatment of diseases of aging

J Med Chem. 2011 Jan 27;54(2):417-32. doi: 10.1021/jm100861p. Epub 2010 Nov 16.
No abstract available

Publication types

  • Review

MeSH terms

  • Aging*
  • Animals
  • Anti-Inflammatory Agents / pharmacology
  • Anti-Inflammatory Agents / therapeutic use
  • Anti-Obesity Agents / pharmacology
  • Anti-Obesity Agents / therapeutic use
  • Catalysis
  • Diabetes Mellitus, Type 2 / drug therapy
  • Drug Evaluation, Preclinical
  • Enzyme Activators / pharmacology
  • Enzyme Activators / therapeutic use
  • Humans
  • Hypoglycemic Agents / pharmacology
  • Hypoglycemic Agents / therapeutic use
  • Kinetics
  • Sirtuin 1 / antagonists & inhibitors
  • Sirtuin 1 / physiology*
  • Substrate Specificity

Substances

  • Anti-Inflammatory Agents
  • Anti-Obesity Agents
  • Enzyme Activators
  • Hypoglycemic Agents
  • Sirtuin 1